Date: Thursday, July 14th, 2011 01:23 pm (UTC)
telegramsam: (boredsherlock)
From: [personal profile] telegramsam
I find this phenomenon particularly hilarious (i.e. depressing), given that even for some mammals with a Y-chromosome, if one tiny bit of that chromosome is damaged or missing or something else disrputs the expression of certain genes on said chromosome during development, the fetus may very well end up phenotypically female because that's the "default setting" for a mammalian fetus...

Date: Friday, July 15th, 2011 06:30 am (UTC)
From: [personal profile] bagpuss
yet that one little bit of Y (SRY if you are interested) attached to any other chromosome and the mammal is male regardless of the presence of Y or not aint genetics weird

Date: Friday, July 15th, 2011 12:01 pm (UTC)
telegramsam: Sarcastic Pee Wee Herman (peeweeblah)
From: [personal profile] telegramsam
True, unless you're dealing with some other mitigating factor (androgen insensitivity, etc).

Which all just proves that even biological sex isn't nearly as cut-and-dried as people assume anyway.

Date: Friday, July 15th, 2011 12:15 pm (UTC)
From: [personal profile] bagpuss
Both fortunately and unfortunately biology is rarely simple, makes for lots of interesting research but does it make it all rather difficult

Date: Friday, July 15th, 2011 12:19 pm (UTC)
telegramsam: Guu twirling (Guutwirl)
From: [personal profile] telegramsam
Platypuses have 10 sex chromosomes, rather than two. :D

Date: Friday, July 15th, 2011 12:21 pm (UTC)
From: [personal profile] bagpuss
Yep but they are also more closely related to the Bird WZ system then the Mammal XY, it would appear our XY system arose from autosomes after we diverged from the monotremes. I think there are bits of X which are syntenic with chr6 in Playtpus

Date: Friday, July 15th, 2011 12:24 pm (UTC)
telegramsam: Guu twirling (Guutwirl)
From: [personal profile] telegramsam
Supposedly one end of the chain is like the mammalian XY system and the other end is more like the WZ system.

Platypuses are awesome.

Date: Friday, July 15th, 2011 12:29 pm (UTC)
From: [personal profile] bagpuss
but a complete bugger to annotate being so far away from any of the evidence

Date: Friday, July 15th, 2011 12:43 pm (UTC)
From: [personal profile] bagpuss
Though if you are interesting in reading the genome paper do let me know

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